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. 2018 Apr 20;39(6):2563–2574. doi: 10.3892/or.2018.6385

Figure 1.

Figure 1.

miR-384 is downregulated in breast cancer tissues, particularly in TNBC, compared with normal breast tissues. (A) Mean expression of miR-384 in breast cancer tissues from GEO58606 (*P<0.05, **P<0.01). (B) Expression of miR-384 in 24 cases of fresh human breast cancer tissues and their adjacent normal tissues by qPCR; miR-384 expression was normalized to U6 and expressed relative to the matched adjacent normal tissues (2−∆∆CT) (T/N, ratio of tumor/normal tissue). (C) Mean expression of miR-384 in normal breast tissues, breast cancer tissue samples and TNBC samples by qPCR (2−∆CT). (D) Mean expression of miR-384 by qPCR according to tumor size (2−∆CT). (E) Mean expression of miR-384 by qPCR according to lymph node metastasis (2−∆CT). Boundaries of boxes stand for the lower and upper quartile. Lines within the boxes and whiskers represent the median and extrema (maximum and minimum). *P<0.05, **P<0.01. TNBC, triple-negative breast cancer.