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. 2018 Apr 5;17(6):7595–7602. doi: 10.3892/mmr.2018.8854

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Copyright: © Tong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Crocin suppressed PDGF-BB-induced ERK/KLF4 signaling activation. (A) Representative images showing the protein expressions of phosphorylated and total ERK1/2 and expression levels of KLF4 protein. Bar graph showing the relative protein levels of (B) phosphorylated ERK1/2 and expression levels of (C) KLF4 in different groups. *P<0.05 vs. control; ^#P<0.05 vs. PDGF-BB. PDGF-BB, platelet-derived growth factor-BB; ERK, extracellular signal regulated kinase; KLF4, kruppel-like factor 4; p-, phosphorylated.