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. 2018 Mar 28;17(6):7497–7504. doi: 10.3892/mmr.2018.8811

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Copyright: © Qi et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — PL-PTX treatment suppresses in vivo growth of ovarian cancer cells within a tumor mouse model. (A) PL-PTX treatment significantly inhibited ovarian tumor growth compared with in the PTX and PBS groups in a 25 d observation. (B) PL-PTX treatment promoted tumor cell apoptosis compared with in the control group. (C) PL-PTX increased the expression levels of caspase-3 and caspase-9 within tumors compared with in the control group. (D) PL-PTX treatment prolonged survival of tumor bearing mice. Magnification, ×40. *P<0.05 and **P<0.01. PL-PTX, pegylated liposomal-paclitaxel.