Figure 1.

Form inhibits proliferation and invasion of SW1116 and HCT116 cells. (A) The structure of Form. (B) NCM460, (C) SW1116 and (D) HCT116 cells were treated with Form concentrations (0, 20, 50, 100 and 200 µM) for 48 h. Cell viability was detected using the MTT assay. Five independent experiments were performed. *P<0.05 or **P<0.01 vs. control (0 µM). (E) Transwell assay demonstrated NCM460, SW1116 and HCT116 cells traversed the filter to the other side, stained using crystal violet solution (magnification, ×400). *P<0.05 or **P<0.01 vs. control (0 µM). Form, formononetin.