Figure 2.

DZX regulates the expression of CHOP, GRP78, caspase-12 and caspase-3 in OGD-treated hippocampal cells. (A) Immunohistochemical staining demonstrated the distribution of GRP78 and CHOP in hippocampal cells exposed to OGD. (B) Western blot analysis was used to detect the expression of GRP78 and CHOP in hippocampal cells exposed to OGD. (C) Protein expression levels of caspase-12 and caspase-3 in hippocampal cells exposed to OGD were detected using western blotting. Data are expressed as the mean ± standard deviation. *P<0.05, as indicated. DZX, diazoxide; CHOP, C/EBP homologous protein; GRP78, 78 kDa glucose-regulated protein; OGD, oxygen-glucose deprivation; 5-HD, 5-hydroxydecanoate.