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. 2018 Apr 23;17(6):8316–8324. doi: 10.3892/mmr.2018.8919

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Copyright: © Guo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Liraglutide treatment ameliorates metabolic disorders in ZDF rats. (A) Body weight and (B) fasting blood glucose were evaluated in ZL rats and ZDF rats with or without liraglutide treatment. Serum levels of (C) ALT and (D) AST were determined in ZL rats and ZDF rats with or without liraglutide treatment. Serum (E) LDL-c and (F) TC levels were examined in ZL rats and ZDF rats with or without liraglutide treatment. Data are presented as the mean ± standard error (n=5 rats for each group). *P<0.05, **P<0.01 and ***P<0.001 vs. ZL; ^#P<0.05 and ^##P<0.01 vs. ZDF+Saline. ZDF, Zucker diabetic fatty; ZL, Zucker lean; ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDL-c, low density lipoprotein cholesterol; TC, total cholesterol.