Table 1. Cohen’s d values, their s.e., P-values and I 2 (heterogeneity) values after meta-analysis for FA differences between schizophrenia patients and healthy controls.
ROI | Cohen’s d | s.e. | P-value | I2 | N voxels |
---|---|---|---|---|---|
Average FA | −0.42 | 0.042 | 4.5 × 10−24 | 34.65 | 112 889 |
ACR | −0.40 | 0.045 | 9.19 × 10−19 | 43.83 | 3129 |
CC | −0.40 | 0.045 | 8.36 × 10−19 | 42.51 | 7318 |
BCC | −0.39 | 0.045 | 2.51 × 10−18 | 43.24 | 3173 |
GCC | −0.37 | 0.042 | 1.24 × 10−18 | 35.22 | 1834 |
ALIC | −0.37 | 0.046 | 2.27 × 10−15 | 46.30 | 1510 |
CR | −0.33 | 0.040 | 3.16 × 10−17 | 27.89 | 7344 |
FXST | −0.32 | 0.042 | 8.28 × 10−14 | 36.39 | 706 |
FX | −0.31 | 0.045 | 6.76 × 10−12 | 43.25 | 222 |
PTR | −0.31 | 0.035 | 1.99 × 10−18 | 11.78 | 1987 |
SS | −0.30 | 0.040 | 4.91 × 10−14 | 30.34 | 1294 |
SFO | −0.29 | 0.054 | 3.96 × 10−8 | 59.68 | 193 |
CGC | −0.27 | 0.045 | 2.95 × 10−9 | 42.87 | 594 |
PCR | −0.25 | 0.036 | 2.39 × 10−12 | 15.76 | 1437 |
SCC | −0.22 | 0.048 | 4.39 × 10−6 | 50.94 | 2311 |
SLF | −0.22 | 0.040 | 5.61 × 10−8 | 29.17 | 3503 |
EC | −0.21 | 0.040 | 1.41 × 10−7 | 31.01 | 2896 |
IC | −0.18 | 0.042 | 1.80 × 10−5 | 36.25 | 4781 |
UNC | −0.16 | 0.033 | 8.78 × 10−6 | 4.18 | 125 |
SCR | −0.15 | 0.034 | 6.91 × 10−6 | 7.84 | 2778 |
RLIC | −0.13 | 0.041 | 0.0021 | 33.10 | 1496 |
IFO | −0.11 | 0.038 | 0.0035 | 22.70 | 88 |
CGH | −0.11 | 0.041 | 0.0082 | 33.73 | 524 |
CST | −0.04 | 0.038 | 0.24 | 24.20 | 167 |
PLIC | 0.04 | 0.046 | 0.37 | 46.20 | 1775 |
Abbreviations: ACR, anterior corona radiata; ALIC, anterior limb of internal capsule; BCC, body of corpus callosum; CC, corpus callosum; CGC, cingulum; CGH, cingulum (hippocampal portion); CR, corona radiata; CST, corticospinal tract; EC, external capsule; FA, fractional anisotropy; FX, fornix; FXST, fornix stria terminalis; GCC, genu of corpus callosum; IC, internal capsule; IFO, inferior fronto occipital fasciculus; PCR, posterior corona radiata; PLIC, posterior limb of internal capsule; PTR, posterior thalamic radiation; RLIC, retrolenticular part of IC; ROI, region of interest; SCC, splenium of corpus callosum; SCR, superior corona radiata; SFO, superior fronto-occipital fasciculus; SLF, superior longitudinal fasciculus; SS, sagittal stratum; UNC, uncinate.