Table 3. Comparison of different cognitive tests between healthy controls and FEP patients.
Test | Cognitive domain |
Mean±s.e.m. |
P-valuea | |
---|---|---|---|---|
Healthy Controls (n=21) | FEP patients (n=40) | |||
CPT-IP | Attention/vigilance | 3.0±0.08 | 2.19 ±0.11 | <0.0001b |
TMT | Speed of processing | 23.2±1.13 | 32.8±2.13 | 0.003b |
BACS-SC | Speed of processing | 61.2±1.18 | 46.0±1.87 | <0.0001b |
Fluency | Speed of processing | 25.2±1.28 | 21.6±0.90 | 0.02 |
WMS-III | Working memory (non-verbal) | 18.5±0.60 | 15.9±0.50 | 0.003b |
LNS | Working memory (verbal) | 15.5±0.55 | 13.3±0.50 | 0.008 |
NAB: MAZES | Reasoning and problem solving | 22.9±0.89 | 19.1±0.88 | 0.007 |
BVMT-R | Visual learning | 29.5±1.10 | 22.4±1.10 | <0.0001b |
MSCEIT | Social cognition | 98.0±1.23 | 89.9±2.0 | 0.007 |
HVLT-R | Verbal learning | 28.7±0.65 | 24.0±0.73 | <0.0001b |
Abbreviations: BACS-SC, Brief Assessment of Cognition in Schizophrenia Symbol Coding; BVMT-R, Brief Visuospatial Memory Test-Revised; CPT-IP, Continuous Performance Test-Identical Pairs; FEP, first-episode psychosis; HVLT-R, Hopkins Verbal Learning Test-Revised; LNS, Letter-Number Span; MSCEIT, Mayer–Salovey–Caruso Emotional Intelligence Test; NAB: MAZES, Neuropsychological Assessment Battery: Mazes; TMT, Trail Making Test; WMS-III, Wechsler Memory Scale-3rd Edition.
Unpaired t-test with equal s.d.
Significant after Bonferroni-corrrection, α-value=0.005.