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. 2017 May 16;23(5):1134–1144. doi: 10.1038/mp.2017.100

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Altered miRNAs in GF-n mice and their relevant Gene Ontology (GO) terms. (a) Number of dysregulated miRNAs based on raw P-value for each experimental comparison. (b) Number of predicted mRNA for individual down-regulated miRNAs in GF-n mice when compared with CON-n that occur in more than 3 prediction algorithms. (c, d) Venn diagram of the number of significant (P_adj) GO terms for biological processes for each miRNA overlapped with significant GO terms from mRNA sequencing. Bar graphs represent a selection of significant terms that were common between mRNA sequencing and enriched from individual mRNAs. (e) Venn diagram showing the number of overlapping miRNAs between groups after fear retention test (CON-fc and GF-fc). CON, conventionally raised mice; CON-fc, CON after fear retention; CON-n, CON naive; GF, germ free; GF-fc, GF after fear retention; GF-n, GF naive.