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. 2017 Jan 24;23(5):1287–1292. doi: 10.1038/mp.2016.252

Figure 2.

Figure 2

Meta-analysis of the association of genetically instrumented use of cannabis and risk of schizophrenia for the 10 single-nucleotide polymorphisms (SNPs) under analysis. Odds ratios (ORs) and 95% confidence intervals (CIs) express the risk of schizophrenia per-1-log unit increase in ever use of cannabis. Meta-analysis uses a fixed effect model. The method to derive the population-based OR of schizophrenia among users of cannabis compared with nonusers (OR 1.37; 95% CI, 1.09–1.67), as presented in the main text and Figure 3, is described in the Supplementary Information.