Table 4.
compounda | IC50 values in µMb | ||
---|---|---|---|
MDA-MB-435 | Ovcar3 | MDA-MB-231 | |
2 | 1.6 | 14.2 | 9.5 |
4 | 14.3 | 17.5 | 24.8 |
7 | 2.0 | 3.6 | 10.8 |
13 | 14.4 | >25 | >25 |
14 | 15.2 | >25 | >25 |
Taxolc | 0.0001 | 0.0015 | 0.17 |
Compounds 1, 3, 5, 6, 8–12, 15–17 were inactive, IC50 values >25 µM.
IC50 is the concentration to inhibit 50% of growth with a 72 h incubation.
Positive control.