Fig. 6.

Theoretical temporal gradients of H₂O₂ in response to 0.1 (filled triangles) and 0.5 mM (open circles) H₂O₂. Gradients are estimated according to Eq. 4. P_s of 0.096 ± 0.034 μm s^− 1 (n = 17) was determined in this work from experiments with OxyR oxidation, giving k_perm = 0.141 ± 0.051 s^− 1 (n = 17). k_catabolism was estimated from the reduction levels of Tpx1 and catalase and rate constants of 1 × 10⁷ M^− 1 s^− 1 and 4.6 × 10⁷ M^− 1 s^− 1, respectively. When Tpx1 and catalase are 100% active in eliminating H₂O₂, k_catabolism = 41 s^− 1, as indicated in Table 2