Table 1.
Characteristics of patients with primary BC, 1993–2013
| Total | Men | Women | ||||
|---|---|---|---|---|---|---|
| n | % | n | % | n | % | |
| Patients with BC | 48,875 | 100 | 39,351 | 100 | 9524 | 100 |
| Period of BC diagnosis | ||||||
| 1993–1997 | 6892 | 14.10 | 5592 | 14.21 | 1300 | 13.65 |
| 1998–2002 | 10,484 | 21.45 | 8377 | 21.29 | 2107 | 22.12 |
| 2003–2007 | 13,585 | 27.80 | 10,942 | 27.81 | 2643 | 27.75 |
| 2008–2013 | 17,914 | 36.65 | 14,440 | 36.70 | 3474 | 36.48 |
| Average age at diagnosis with BC (years; mean, SD) | 65.39 | 12.46 | 64.81 | 12.20 | 67.80 | 13.22 |
| Median age at diagnosis with BC (years; median, range) | 67 | 105 (1–106) | 66 | 100 (1–101) | 70 | 105 (1–106) |
| Age at primary BC diagnosis (years) | ||||||
| 0–39 | 1608 | 3.29 | 1259 | 3.20 | 349 | 3.66 |
| 40–59 | 12,489 | 25.55 | 10,601 | 26.94 | 1888 | 19.82 |
| ≥60 | 34,778 | 71.16 | 27,491 | 69.86 | 7287 | 76.51 |
| Percentage of primary treatment status | ||||||
| Surgery | 42,448 | 86.85 | 34,653 | 88.06 | 7795 | 81.85 |
| Radiation | 1298 | 2.66 | 1004 | 2.55 | 294 | 3.09 |
| Chemotherapy | 6161 | 12.61 | 5045 | 12.82 | 1116 | 11.72 |
| Average follow-up after BC diagnosis (years; mean, SD) | 5.65 | 5.09 | 5.70 | 5.06 | 5.46 | 5.21 |
| Median follow-up after BC diagnosis (years; median, range) | 4.13 | 20.80(0–20.80) | 4.21 | 20.80(0–20.80) | 3.67 | 20.80(0–20.80) |
| Number of patients who developed a SPC | 3495 | 7.15 | 3116 | 7.92 | 379 | 3.98 |
| Average age at SPC diagnosis (years; mean, SD) | 70.57 | 9.28 | 70.71 | 8.94 | 69.40 | 11.67 |
| Median age at SPC diagnosis (years; median, range) | 71(10–95) | 71.5(10–95) | 71(12–93) | |||
| Average interval between primary cancer and SPC (years; mean, SD) | 5.23 | 4.30 | 5.18 | 4.29 | 5.75 | 4.39 |
| Median interval between primary cancer and SPC (years; median, range) | 4.17(0.17–0.67) | 4.08(0.17–20.67) | 4.75(0.17–19.08) | |||
| Number of patients by latency between primary cancer and SPC (years) | ||||||
| 1 | 556 | 15.91 | 469 | 12.95 | 47 | 16.19 |
| 1–4 | 1409 | 40.31 | 1176 | 39.67 | 144 | 40.61 |
| 5–9 | 1000 | 28.61 | 813 | 29.20 | 106 | 28.07 |
| ≥10 | 530 | 15.16 | 438 | 18.18 | 66 | 15.12 |
| Number of patients by age at SPC diagnosis (years) | ||||||
| 0–39 | 13 | 0.37 | 8 | 0.26 | 5 | 1.32 |
| 40–59 | 396 | 11.33 | 327 | 10.49 | 69 | 18.21 |
| ≥60 | 3086 | 88.30 | 2781 | 89.25 | 305 | 80.47 |
| Average follow-up after SPC diagnosis, (years; mean, SD) | 2.55 | 2.91 | 2.48 | 2.82 | 3.10 | 3.52 |
| Median follow-up after SPC diagnosis (years; median, range) | 1.42 | 20.00(0–20.00) | 1.42 | 20.00(0–20.00) | 1.67 | 19.50(0–19.50) |
| Number of subsequent primary cancers | ||||||
| 1 | 3259 | 6.67 | 2896 | 7.36 | 363 | 3.81 |
| 2 | 217 | 0.44 | 203 | 0.52 | 14 | 0.15 |
| ≥3 | 19 | 0.04 | 17 | 0.04 | 2 | 0.02 |
BC: bladder cancer, SD: standard deviation, SPC: second primary cancer