Skip to main content
. 2018 May 14;115(22):E5076–E5085. doi: 10.1073/pnas.1718902115

Fig. 5.

Fig. 5.

Systemic IL-23 administration induces resolution of DSS-induced colonic damage in Il1rl2−/− mice. (A) DAI of Il1rl2+/+ and Il1rl2−/− mice treated with DSS for 5 d, followed by normal water for 7 d, in the presence or absence of IL-23. (B and C) Image and length of colons from mice treated as in A. (Scale bar, 1 cm.) The H&E staining (D) and histology scoring (E) of colon sections from mice treated as in A are shown. (Scale bar, 100 μm.) Data are representative of three independent experiments with four to five mice per group. All data are presented as mean ± SEM (one-way ANOVA with Tukey’s multiple comparison test: *P < 0.05; **P < 0.01). n.s., not significant.