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EGFR activation plays an important role in regulating protective autophagy in anoikis-resistant GSCs. Inhibition of EGFR activation leads to increased autophagy. Effect of erlotinib on (A) GSC survival and (B) expression of autophagy markers ATG5, LC3B, and Lamp1. Error bars indicate ±SD, *P < 0.05. (Magnification: 100×.)
