FIG. 7.

Transmission electron micrographs showing significantly greater density of forming elastic fibers in cBM-SMC cultures, and less so in rBM-SMC cultures relative to RASMC cultures. The elastic fibers were composed of fibrillin microfibrils (white arrows) laid down as a prescaffold onto which amorphous elastin (red arrows) was deposited and crosslinked. The RASMC cultures contained mainly amorphous elastin deposits. Very few amorphous elastin deposits and no fiber-like structures were seen in EaRASMC cultures.