FIG. 7.

Histology of critical-size defect regeneration. Movat's pentachrome staining after 8 weeks of 0 and 400 μm/s construct implantation in the critical-size femoral defect. The defect is represented by the dashed lines, where yellow represents bone, and light red represents fibrous tissue. Magnified images of the construct-native bone interface were taken, with the black rectangle indicating the location of the interface within the defect. The white arrows represent the original decellularized bone, indicated by the empty cellular lacunae. Black arrows indicate formed bone, with FT indicating the fibrous tissue that is impeding integration. Scale bars: defect 500 μm, interface 50 μm. Color images available online at www.liebertpub.com/tea