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. 2017 Sep 8;16:643–658. doi: 10.1016/j.nicl.2017.09.003

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© 2017 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 6 — Effects of intensity correction and registration of synthetic images on a (top) pathology free and (bottom) pathological subject. (A) FLAIR image. (B) Rigidly registered synthetic image. (C) Difference image from (A) to (B). (D) Rigidly registered intensity corrected synthetic image. (E) Difference image from (A) to (D). (F) FFD registered intensity corrected synthetic image. (G) Difference image from (A) to (F). Note that the intensity correction and FFD registration do not prevent detection of the pathology (arrows).