Table 3. Comparison of symptoms post fecal microbiota transplantation (FMT) for patients with and without underlying inflammatory bowel diseases (IBD).
Gastrointestinal (GI) symptoms include one or more of the following: abdominal pain, fever, abdominal distension, or bloody stool. (The categorical variables were compared using Fisher’s Exact test due to the small sample and the continuous variables were evaluated using Wilcoxon two independent sample test.)
| Variable | No underlying IBD (n = 10, 66%) | Underlying IBD (n = 5, 33%) | p-value |
|---|---|---|---|
| Age, median(IQR) | 6.55(8.01) | 8.02(2.61) | 0.4053 |
| Gender male% | 5(50) | 2(40) | 1.0000 |
| GI symptoms prior to FMT (yes, %) | 9(90) | 5(100) | 1.0000 |
| GI symptoms at 24-hour post FMT | 0.5055 | ||
| No | 3(30) | 0(0) | |
| Yes | 7(70) | 4(100) | |
| GI symptoms at 1-week post FMT | 0.0667 | ||
| No | 1(12.5) | 3(75) | |
| Yes | 7(87.5) | 1(25) | |
| GI symptoms at 1-month post FMT | 0.2657 | ||
| No | 3(37.5) | 4(80) | |
| Yes | 5(62.5) | 1(20) | |
| GI symptoms at 3 months post FMT | 1.0000 | ||
| No | 2(28.6) | 1(20) | |
| Yes | 5(71.4) | 4(80) | |
| Route of FMT | 0.3333 | ||
| Colonoscopy | 10(100) | 4(80) | |
| NJ Tube | 0 | 1(20) | |
| Number of antibiotic courses prior to FMT, median(IQR) | 2.5(2) | 4(2) | 0.6217 |
| Number of ED visits within a year of FMT, median(IQR) | 1.5(3) | 4(3) | 0.0468 |
| Number of CDI episodes, median(IQR) | 3(1) | 3(0) | 0.9456 |
| B:F Ratio, median(IQR) | 0.0021(0.0068) | 0.0030(0.0027) | 0.8209 |
| Clostridia Distribution, median (IQR) | 0.0055(0.0127) | 0.00001(0.0109) | 0.4102 |