Table 2.

Factors associated with receiving adequate contraceptive coverage during isotretinoin treatment among women aged 15–45 years, Estonia, 2012–2016

	Not/partially covered with contraception	Covered with contraception	Proportion (%) of those fully covered	Univariate models				Adjusted model
				OR	95% CI		p value	OR	95% CI		p value
Age (years)
15–19	922	39	4.1	0.19	0	0.27	0	0.18	0.13	0.26	0
20–29	998	222	18.2	1				1
30–39	340	144	29.8	1.90	0	2.428	0	1.94	1.52	2.48	0
40–45	93	34	26.8	1.64	0	2.499	0	1.70	1.11	2.60	0.014
Diagnosis
Acne	2228	393	15.0	1
Other	125	46	26.9	2.09	1.46	2.97	0
Specialty of prescribing physician
Dermatovenerologist	2249	413	15.5	1
Other	39	13	25.0	1.82	0.96	3.43	0.066
Family physician	65	13	16.7	1.09	0.59	1.99	0.782
Mean daily dose of isotretinoin (SD)
	36.8	35.3		0.99	0.99	1.00	0.067
	16.3	17.3
The year of treatment episode (beginning)
2012	760	104	12.0	1				1
2013	466	85	15.4	1.33	0.98	1.82	0.068	1.35	0.98	1.85	0.07
2014	392	77	16.4	1.44	1.04	1.97	0.026	1.45	1.04	2.02	0.03
2015	403	98	19.6	1.78	1.31	2.40	0	1.78	1.30	2.44	0.00
2016	332	75	18.4	1.65	1.19	2.28	0.002	2.03	1.44	2.86	0.00
Mean duration of the treatment episode (months) (SD)
	4.6	4.7		1.02	0.97	1.07	0.363	1.07	1.02	1.13	0.01
	2.0	2.1

Statistically significant values are in bold