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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Curr Opin Neurobiol. 2018 Feb 22;50:109–118. doi: 10.1016/j.conb.2018.02.003

Figure 3.

Figure 3

Genetic access to cell types in the mouse brain. A. Binary system for cell type targeting using single driver. B. Intersectional targeting paradigms. C. Besides marker gene expression, other cellular features including developmental lineage, anatomical location and connectivity can also be utilized to target specific cell types within broad classes of neural stem cells, neurons and glia. For example, retrograde virus can be combined with Cre driver mice to label cells expressing a specific marker and also projecting to a specific target brain region.