Figure 3.
(A) Photograph of gradient separation in U87 cells with arrow indicating low density lipid raft band corresponding to survivin-containing fraction #4. Western blot detection of lipid raft-associated proteins and survivin in subcellular fractions derived from U87 (B) and A1207 (C) glioblastoma cells. (D) Transiently expressed recombinant c-Myc-tagged human survivin in association with lipid raft protein fractions in HEK293T cells detected with an anti-c-Myc-tag antibody (9E10). (E) Imagestream imaging flow cytometric visualization of co-localized bound cholera toxin B (CT-B) and survivin in lipid rafts.
