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Overall survival of patients with localized osteosarcoma based on LC3B+ puncta status or HSP27 expression status at resection. A. Stratified by cytoplasmic LC3B+ puncta status (≥10% [positive] vs < 10% [negative]). The presence of LC3B+ puncta at resection was associated with better OS. B. Stratified by HSP27 expression status (≥10% [positive] vs <10% [negative]). HSP27 expression was associated with worse OS. P values were calculated with a log-rank test.
