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(A) I-V plots and (B) peak current density for WT KCNQ1/KCNE1 following treatment with ISO (100 nM for 12-24 hours) and CN21, CN21-Ala, or myr-PKI. (C) Normalized activation curves following ISO with CN21, CN21-Ala, or myr-PKI. (D) Immunoblots and percent changes in CaMKII and CaMKII T287 phosphorylation following 100 nM ISO for 24 hours. *p<0.05
