Table 3.
Odds ratios for molecular characteristics for linked invasive cases.
| Screen-detected (N=165) |
Interval (N=205) |
Adjusted OR (95% CI)a |
|
|---|---|---|---|
| N (%) | N (%) | ||
| 3-marker subtype | |||
| Luminal A | 99 (68) | 102 (55) | 1.00 |
| Luminal B | 14 (10) | 16 (9) | 0.95 (0.43, 2.08) |
| HER2 | 6 (4) | 7 (4) | 1.12 (0.36, 3.45) |
| Triple negative | 26 (18) | 60 (32) | 2.45 (1.10, 5.47) |
| Missing | 20 | 20 | |
| 5-marker subtype | |||
| Luminal A | 67 (64) | 64 (47) | 1.00 |
| Luminal B | 12 (12) | 30 (22) | 2.45 (1.14, 5.25) |
| HER2 | 6 (6) | 4 (3) | NRb |
| Basal-like | 19 (18) | 38 (28) | 2.06 (1.07, 3.95) |
| Missing | 61 | 69 | |
| PAM50 | |||
| Luminal A | 51 (71) | 46 (46) | 1.00 |
| Luminal B | 4 (6) | 18 (18) | NRb |
| HER2 | 5 (7) | 8 (8) | 1.82 (0.54, 6.15) |
| Basal-like | 12 (17) | 29 (29) | 2.68 (1.21, 5.94) |
| Missing | 93 | 104 | |
| PAM50 | |||
| Luminal A | 51 (71) | 46 (46) | 1.00 |
| Non-Luminal A | 21 (29) | 55 (54) | 2.94 (1.52, 5.71) |
| Missing | 93 | 104 | |
| p53 | |||
| Wild type | 42 (55) | 55 (52) | 1.00 |
| Mutant | 34 (45) | 51 (48) | 1.13 (0.63, 2.05) |
| Missing | 89 | 99 | |
| ROR-PTc | |||
| Low/Medium | 68 (96) | 81 (77) | NRb |
| High | 3 (4) | 24 (23) | NRb |
| Missing | 94 | 100 |
a
All odds ratios are adjusted for age and menopausal status.
b
Odd ratios are not reported where cell size < 5 observations.
c
PAM50 risk of recurrence score.