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. 2018 Jun 1;19:424. doi: 10.1186/s12864-018-4826-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — a The heatmap depicting the methylation and expression patterns of DMRs commonly detected in all blastocyst groups. DM; differentially methylated, DE; differentially expressed. The red color indicates hypermethylation of the DNA methylation or upregulation of the mRNA expression whereas the green color indicates hypomethylation of the DNA methylation or downregulation of the mRNA expression. b The gene network and biological processes enriched by commonly detected DMRs and which showed inverse correlation with their corresponding mRNA expression levels