Table 3.
Cox proportional hazard model analysis of clinico-pathological factors associated with LPLN metastasis
| Factor | Odd ratio (95% C.I.) | p value |
|---|---|---|
| Gender (female/male) | 2.25 (0.48–10.5) | 0.02 |
| Serum CEA ng/mL (> 5/≤ 5) | 2.17 (0.39–12.6) | 0.06 |
| Clinical T stage (T4/T3) | 3.23 (0.69–15.21) | 0.04 |
| Regional nodes on MRI (positive/negative) | 2.53 (0.54–11.85) | 0.01 |
| LPLN (enlarged/negative) | 8.27 (1.41–48.53) | 0.0001 |
| Annularity (> 2/3/≥ 2/3) | 0.5 (0.11–2.19) | 0.9 |
| pT stage (T4/T2-T3) | 1.67 (0.37–7.48) | 0.07 |
| pN stage (N+/N-) | 2.22 (0.49–10.16) | 0.02 |
| Tumour differentiation (moderate or poor/well) | 1.91 (0.34–10.68) | 0.09 |
| LVI (present/absent) | 4.18 (0.88–19.92) | 0.001 |
| Size (≥ 5 cm/< 5 cm) | 2.76 (0.5–15.29) | 0.01 |
| Distance from anal verge (< 5 cm/≥ 5 cm) | 1.79 (0.41–7.86) | 0.08 |