Table 2.
Recurrence and metastasis rates based on the treatment type
| Study name | Number of patients | Local recurrence rate | Metastasis rate | Follow-up mean (range, years) |
|---|---|---|---|---|
| Simon et al. [24] | ||||
| Limb salvage | 227 | 10.9% | 58.9% | 5.54 (not reported) |
| Above knee amputation | 7.8% | 56.5% | ||
| Hip disarticulation | 0% | 53.8% | ||
| Mavrogenis et al. [27] | ||||
| Limb salvage | 46 | 13% | N/A | 5 (0.75–24) |
| Amputation | 0% | N/A | ||
| Total | 6.5% | 9.5% | ||
| Bacci et al. [26] | ||||
| Limb salvage | 560 | 6.4% | N/A | 10.5 (5–17) |
| Amputation | 4.2% | N/A | ||
| Total | 5.3% | 33.5% | ||
| Jeys et al. [36] | ||||
| Limb salvage | 776 | 5.4% | N/A | 9 (10–35) |
| Unwin et al. [41] | ||||
| Limb salvage | 1001 | 5.4% | N/A | 3.8 (not reported) |
| Mean | ||||
| Limb salvage | 2610 | 8.2% (±3.5) | 33% (±24.7) | |
| Amputation | 3% (±3.7) | 38% (±21.7) | ||