Table 3.

Normal Mode Analysis Results for Respective Complexes of the Enterovirus 71 Viral Capsid

Complex	Number of Residues	Total Number of Nontrivial Modes (3N-6)a	Mode Identified to Overlap Capsid Expansion	Maximum Overlap
Protomer	842	2520	1	0.24
			6a	0.18
Protomer CG4	209	621	1	0.34
			4	0.28
Pentamer	4210	12,624	3b∗	0.71∗
Pentamer CG4	1045	3129	3∗	0.71∗
Pentamer interface	12,630	37,884	17c∗	0.71∗
Pentamer interface CG4	3135	9399	17∗	0.70∗
Capsid CG4	12,540	37,614	27d	0.67
			75e∗	0.53∗
			113f	0.20
			combination	0.80
Capsid CG12	4320	12,954	27	0.64
			75∗	0.60∗
			121	0.20
			combination	0.77

NMA results for respective complexes of the EV71 viral capsid. Maximum overlapping modes with capsid expansion, as determined from the experimental structures, were identified. A common mode was identified across the pentamer, pentamer interface complex, and coarse-grained capsid structures. This common mode is indicated with an asterisk. Movies of the respective capsid complexes are in the Supporting Material.

^aMovie S1.

^bMovie S2.

^cMovie S3.

^dMovie S4.

^eMovie S5.

^fMovie S6.