Figure 7.

Prediction of hydrodynamic properties for a disordered protein ensemble. Shown are the effective translational hydrodynamic radii of disordered protein structures calculated using HullRad (dark gray, blue online) or HYDROPRO (light gray, red online). The structures are sorted by compactness using the anhydrous R_G calculated using Eq. 13. Three example structures representing different degrees of compactness are shown as atomic sphere models. The ensemble contains 575 generated structures of α-synuclein from the Protein Ensemble Database (accession number PED9AAC). To see this figure in color, go online.