Table 1.
CD Results of Colistin in Water and Membrane Mimics
| Colistin Sample | α-Helix-Type % | β-Sheet % | β-Turn % | Random Coil % | R2 |
|---|---|---|---|---|---|
| Water | 0 ± 1 | 48 ± 6 | 16 ± 5 | 36 ± 8 | 0.88 |
| G(−) | 24 ± 6 | 18 ± 8 | 0 ± 1 | 59 ± 7 | 0.99 |
| G(+) | 17 ± 3 | 17 ± 4 | 2 ± 1 | 64 ± 2 | 0.99 |
| LPS | 31 ± 11 | 3 ± 3 | 0 ± 1 | 67 ± 3 | 0.99 |
| Eukaryotic | 30 ± 10 | 9 ± 8 | 0 ± 1 | 62 ± 12 | 0.99 |
Percent composition was obtained by normalizing to 100% the unitless coefficients in the linear least squares fit of the structural motifs to the data. R2 values indicate goodness of fit, with 1 indicating a perfect fit to the data.