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. Author manuscript; available in PMC: 2019 Jun 1.

Published in final edited form as: Acta Biomater. 2018 Apr 10;73:112–126. doi: 10.1016/j.actbio.2018.04.003

Macrophage polarization 3 days after hydrogel injection. M: muscle, G: hydrogel, Arrows: foreign body capsule. (a) CD86 (green) and CD68 (red) staining. (b) CD206 (green) and CD68 (red) staining. (c) CD86 (green)/CD68 (red) and (d) CD206 (green)/CD68 (red) staining at the hydrogel/muscle interface. (e, f) Percentage of CD86⁺ and CD206⁺ cells in CD68⁺ population, respectively. (g) Ratio between CD86⁺ and CD206⁺ cells in CD68⁺ population. * Significant difference, p < 0.05.

Macrophage polarization 3 days after hydrogel injection. M: muscle, G: hydrogel, Arrows: foreign body capsule. (a) CD86 (green) and CD68 (red) staining. (b) CD206 (green) and CD68 (red) staining. (c) CD86 (green)/CD68 (red) and (d) CD206 (green)/CD68 (red) staining at the hydrogel/muscle interface. (e, f) Percentage of CD86⁺ and CD206⁺ cells in CD68⁺ population, respectively. (g) Ratio between CD86⁺ and CD206⁺ cells in CD68⁺ population. * Significant difference, p < 0.05.