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. 2018 Jan 31;10:100–108. doi: 10.1016/j.molmet.2018.01.020

Figure 4.

Figure 4

Oral galanin improves insulin sensitivity via an AMPK signaling. (A) Hepatic glycogen content of fed mice after an oral administration of water (HFD Control) or galanin 100 nM during one week. n = 4–10 per group. *p < 0.05 vs HFD Control. (B) Relative expression of glucose-6-phosphatase (G6pase) mRNA in liver of HFD mice after an oral administration of water (HFD Control) or galanin 100 nM during one week. n = 4–5 per group. (C) Relative expression of Phosphoenolpyruvate carboxykinase (Pepck) mRNA in liver of HFD mice after an oral administration of water (HFD Control) or galanin 100 nM during one week. n = 4–5 per group. (D)Vastus lateralis muscle glycogen content of fed HFD mice after an oral administration of water (HFD Control) or galanin 100 nM during one week. n = 4–10 per group. *p < 0.05 vs HFD Control. (E) Relative expression of glucose transporter type 4 (Glut-4) mRNA in vastus lateralis muscle of HFD mice after an oral administration of water (HFD Control) or galanin 100 nM during one week. n = 5 per group. (F)Vastus lateralis muscle AMPK and Akt protein expression of HFD mice after an oral administration of water (HFD Control) or galanin 100 nM during one week and the relative quantification. n = 4–5 per group. *p < 0.05 vs Control.