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. 2018 May;6(9):162. doi: 10.21037/atm.2018.05.07

Table 3. Stability of variant allele fractions across DNA input levels for the low input library preparation.

Gene Mutation.AA 0.1 ng/ìL 0.5 ng/ìL 1 ng/ìL 5 ng/ìL
EGFR p.E746_A750del 0.78 0.81 0.83 0.84
BRAF p.V600E 0.11 0.10 0.09 0.10
KRAS p.G12V 0.64 0.66 0.64 0.54