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Hyperglycemia induces apoptosis in cultured SH-SY5Y cells. (A) Representative fluorescence micrographs of DAPI staining of SH-SY5Y cells exposed to 5.5 mM (CON), 75 mM glucose (HG), or mannitol (MAN) for 96 h. The representative apoptotic cells were marked by arrows. Scale bar: 20 µm. (B) Percentage quantification of apoptotic cells. ***P<0.001 versus control.
