Figure 3.

Abnormal EEG and Epileptiform Activities in Otud7a-Null Mice

Representative EEG traces from the parietal and frontal cortices of one WT (A) and four different null (B–E) mice. Red lines indicate the abnormal repetitive-spike events (B) or seizure-like events manifesting phenotypically as behavioral arrest (C–E). The seizure-like events lasted for 9.11 ± 0.98 s. The spike amplitude and frequency were 0.42 ± 0.02 mV and 4.77 ± 0.22 Hz, respectively. The data were obtained from 23 events in 3 mice and presented as mean ± SEM. Note, the data were also presented in Table 2 for each mouse. Abbreviations: PC, parietal cortex; FC, frontal cortex.