Table 1.

Differential expression of specific C. difficile genes during biofilm growth (pairwise comparison).

Gene	Description	Biofilm/plate differential expression log2(fold change)	Biofilm/planktonic differential expression log2(fold change)
pilA1	Major pilin	−0.90	0.87*
pilA2	Predicted pilin	−3.12*	−0.41
pilA3	Predicted pilin	−2.17	0.37
pilJ	Minor pilin	0.43	0.07
pilK	Pilin-like protein	1.02*	1.18*
pilU	Pilin-like protein	1.04*	1.08*
pilV	Pilin-like protein	1.60*	0.96*
pilW	Pilin-like protein	−0.27	−0.60*
pilX	Pilin-like protein	−2.21	−0.26
fliC	Flagellin	−0.25	−1.35*
cwp66	Adhesin (cell-wall protein)	−1.73*	−0.18
cwp84	Cysteine protease important for surface layer maturation	0.37	−0.31
CD0802	Adhesin (lipoprotein)	4.87*	−0.87*
luxS	Quorum-sensing regulator	1.99	0.12
Spo0A	Transcription factor controlling spore formation	−1.35	−0.23
tcdA	Toxin A	−1.70*	0.02
tcdB	Toxin B	−1.53*	0.59*
sigB	Housekeeping gene	−0.26	−0.34

^*Statistically significant (q-value < 0.05).