Table 2.
Patients’ operative and postoperative characteristics
| Variable | No delirium ≥65 years (n=1,413) | Delirium ≥65 years (n=384) | p-value | No delirium ≥80 years (n=153) | Delirium ≥80 years (n=77) | p-value |
|---|---|---|---|---|---|---|
| Operative risk | ||||||
| EuroScore logistic, mean ± SD | 9.64±10.51 | 12.66±12.22 | <0.001 | 17.71±13.47 | 18.46±13.44 | NS |
| EuroScore logistic 2, mean ± SD | 3.53±5.01 | 4.58±5.49 | <0.001 | 4.64±4.56 | 5.21±5.73 | NS |
| Operation type | ||||||
| Isolated CABG, n (%) | 880 (62.28) | 211 (54.95) | 0.009 | 77 (50.33) | 45 (58.44) | NS |
| CABG + valve, n (%) | 245 (17.34) | 106 (27.60) | <0.001 | 34 (22.22) | 20 (25.97) | NS |
| CABG + AAA, n (%) | 20 (1.42) | 6 (1.56) | NS | 0 (0.00) | 1 (1.30) | NS |
| TAVI, n (%) | 24 (1.70) | 4 (1.04) | NS | 18 (11.76) | 2 (2.60) | 0.019 |
| Aortic aneurysm, n (%) | 66 (4.76) | 16 (4.17) | NS | 4 (2.61) | 3 (3.90) | NS |
| Valve, n (%) | 178 (12.60) | 41 (10.68) | NS | 20 (13.07) | 6 (7.79) | NS |
| Case priority | ||||||
| Planned, n (%) | 1,028 (72.75) | 279 (72.66) | 94 (61.44) | 48 (62.34) | ||
| Urgent, n (%) | 311 (22.01) | 81 (21.09) | NS | 52 (33.99) | 20 (25.97) | NS |
| Emergent, n (%) | 74 (5.24) | 24 (6.1) | 7 (4.58) | 9 (11.69) | ||
| Intraoperative data | ||||||
| CPB time (min), mean ± SD | 66.94±50.40 | 71.13±31.23 | 0.009 | 64.40±27.91 | 68.30±28.82 | NS |
| Aortic cross-clamping (min), mean ± SD | 44.02±24.46 | 48.14±25.78 | 0.003 | 44.61±23.83 | 46.72±24.13 | NS |
| Reperfusion time (min), mean ± SD | 16.58±9.68 | 16.97±9.05 | NS | 14.96±6.98 | 16.81±11.02 | NS |
| Postoperative data | ||||||
| Drainage (mL) | 485±528 | 529±477 | 0.04 | 438±416 | 535±543 | NS |
| Highest creatinine (mg/dL) | 1.41±0.87 | 1.86±1.29 | <0.001 | 1.63±0.84 | 1.86±1.08 | NS |
| Lowest GFR (mL/min/1.73 m2) | 57.27±23.71 | 45.54±24.37 | <0.001 | 43.06±18.52 | 39.78±20.40 | NS |
| Transfusions | ||||||
| PRBCs (mL) | 954±852 | 1,047±847 | 0.03 | 1,024±879 | 1,126±904 | NS |
| FFP (mL) | 929±715 | 927±504 | NS | 872±411 | 932±563 | NS |
| Platelets (mL) | 353±182 | 366±153 | NS | 339±147 | 381±184 | NS |
| Postoperative complications | ||||||
| Stroke, n (%) | 53 (3.75) | 19 (4.95) | NS | 12 (7.84) | 0 (0) | 0.027 |
| Atrial fibrillation, n (%) | 324 (22.93) | 131 (34.11) | <0.001 | 42 (27.45) | 30 (38.96) | NS |
| Low cardiac output, n (%) | 56 (3.96) | 14 (3.65) | NS | 4 (2.61) | 2 (2.60) | NS |
| Respiratory failure, n (%) | 133 (9.41) | 84 (21.88) | <0.001 | 24 (15.69) | 17 (22.08) | NS |
| Pneumonia, n (%) | 42 (2.97) | 45 (11.72) | <0.001 | 6 (3.92) | 10 (12.99) | 0.011 |
| Acute kidney injury, n (%) | 39 (2.76) | 25 (6.51) | <0.001 | 9 (5.88) | 7 (9.09) | NS |
| AKI with CRRT, n (%) | 160 (11.31) | 93 (24.22) | <0.001 | 28 (18.30) | 18 (23.38) | NS |
| Sepsis, n (%) | 7 (0.5) | 1 (0.26) | NS | 1 (0.65) | 6 (7.79) | NS |
Abbreviations: AAA, ascending aorta aneurysm; AKI, acute kidney injury; CABG, coronary artery bypass grafting; GFR, glomerular filtration rate; CPB, cardiopulmonary bypass; CRRT, continuous renal replacement therapy; FFP, fresh frozen plasma; n, number of patients; NS, not significant; PRBCs, packed red blood cells; TAVI, transcatheter aortic valve implantation.