Table 2.
Outcomes of PR in 117 completed stages according to the occurrence (EX group) or nonoccurrence (NEX group) of a COPD exacerbation
| Variable | EX group (n=27)
|
NEX group (n=90)
|
P-value
|
||||
|---|---|---|---|---|---|---|---|
| Before PR | After PR | Before PR | After PR | Between patients (grouping variable: exacerbation) | Within patients (repeated measure) | Interaction of factors | |
| BODE index | 5.4±2.3 | 4.2±1.9 | 3.3±1.9 | 2.3±1.8 | <0.001 | <0.001 | 0.460 |
| FVC, % pred | 75.2±19.1 | 74.1±17.9 | 78.8±22.6 | 81.9±22.6 | 0.246 | 0.499 | 0.048 |
| FEV1, % pred | 41.9±19.9 | 41.2±18.7 | 49.0±20.1 | 51.0±21.2 | 0.068 | 0.696 | 0.064 |
| 6MWT, m | 320±101 | 354±101 | 379±85 | 442±97 | <0.001 | <0.001 | 0.019 |
| VO2 peak, mL/kg/min | 11.9±3.4 | 13.6±4.7 | 13.5±3.8 | 14.8±5.4 | 0.421 | 0.013 | 0.860 |
| WR peak, W | 42.1±17.9 | 56.7±20.1 | 64.0±23.5 | 75.4±28.3 | 0.001 | <0.001 | 0.512 |
| mMRC score | 2.9±0.8 | 2.0±0.9 | 2.0±0.9 | 1.4±0.8 | <0.001 | <0.001 | 0.176 |
| HADS score | 16.0±6.2 | 12.6±5.7 | 15.0±6.5 | 11.3±6.0 | 0.305 | <0.001 | 0.712 |
| CAT score | 23.0±5.4 | 21.0±6.0 | 19.6±6.6 | 15.4±6.6 | <0.001 | <0.001 | 0.111 |
| VSRQ score | 31.2±15.4 | 39.3±14.8 | 36.6±12.7 | 49.7±14.2 | 0.004 | <0.001 | 0.093 |
Note: Data are presented as mean ± SD.
Abbreviations: 6MWT, 6-minute walk test; BODE index, body mass index, airway obstruction, dyspnea, exercise capacity; CAT, COPD Assessment Test; HADS, Hospital Anxiety and Depression Scale; mMRC, modified Medical Research Council; % pred, percent predicted; PR, pulmonary rehabilitation; VO2 peak, peak oxygen uptake; VSRQ, visual simplified respiratory questionnaire; WR peak, peak work rate.