Table 4.

Sensitivity, specificity, optimal threshold value, and AUC for the BODE, DOSE, SCOPEX indices, and NEXA as predictors of the occurrence of an AECOPD during pulmonary rehabilitation

	Sensitivity (95% CI)	Specificity (95% CI)	Optimal threshold value	AUC (95% CI)	P-value
BODE index	78.1 (60.0–90.7)	73.6 (64.1–81.7)	>4	0.776 (0.692–0.845)	<0.0001
DOSE index	21.9 (9.3–40.0)	87.1 (78.5–93.2)	>4	0.504 (0.413–0.594)	0.952
SCOPEX index	84.4 (67.2–94.7)	51.6 (41.0–62.1)	>39	0.738 (0.652–0.813)	<0.0001
NEXA	56.3 (37.7–40.0)	66.7 (56.1–76.1)	>1	0.632 (0.541–0.717)	0.02

Abbreviations: AECOPD, acute exacerbation of COPD; AUC, area under the receiver operating characteristics curve; BODE, body mass index, airway obstruction, dyspnea, exercise capacity; DOSE, dyspnea, obstruction, smoking, exacerbation; NEXA, number of AECOPD episodes in the year preceding enrolment; SCOPEX, score to predict short-term risk of COPD exacerbations.