Table 3.

Univariate log-rank analyses

Parameters	Category	No of cases	DSS		DMFS		LRFS
			No of events	p-value	No of events	p-value	No of events	p-value
Gender	Male	95	45	0.7870	38	0.6128	30	0.3240
	Female	29	14		11		7
Age (years)	<60	98	48	0.8600	42	0.3091	29	0.8206
	≥60	26	11		7		8
Primary tumor (T)	T1–T2	80	32	0.0289*	25	0.0085*	19	0.0180*
	T3–T4	44	27		24		18
Nodal status (N)	N0–N1	56	18	0.0008*	17	0.0132*	12	0.0160*
	N2–N3	68	41		32		25
Stage	I–II	38	10	0.0020*	9	0.0072*	5	0.0026*
	III–IV	86	49		40		32
Histological grade	Keratinized/non-keratinized	47	20	0.1980	17	0.2753	15	0.9521
	Undifferentiated	77	39		32		22
Periostin	Low expression (H-score<median)	62	20	0.0002*	20	0.0138*	13	0.0028*
	High expression (H-scor≥median)	62	39		29		24

Note:

^*Statistically significant.

Abbreviations: DMFS, distal metastasis-free survival; DSS, disease-specific survival; LRFS, local recurrence-free survival.