Table 4.

Multivariate survival analyses

Parameter	Category	DSS			DMFS			LRFS
		HR	95% CI	p-value	HR	95% CI	p-value	HR	95% CI	p-value
Stage	I–II	1			1			1
	III–IV	2.235	1.113–4.488	0.024*	2.275	1.086–4.767	0.029*	2.210	1.222–8.316	0.018*
Periostin exp.	Low exp.	1			1			1
	High exp.	2.311	1.327–4.027	0.003*	1.727	0.962–3.100	0.067	3.187	1.108–4.408	0.024*

Note:

^*Statistically significant.

Abbreviations: DSS, disease-specific survival; DMFS, distal metastasis-free Survival.