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. Author manuscript; available in PMC: 2018 Jun 4.
Published in final edited form as: Mol Cell Endocrinol. 2017 Jun 2;454:50–68. doi: 10.1016/j.mce.2017.05.037

Figure 4. Developmental uncoupling of hepcidin genes, Hepc and Hamp2.

Figure 4

(A) Hepcidin (Hamp/Hepc) expression (Cy3) at birth (PN0) and at weaning (PN21). Fold change values are shown from EDGE3 processed data. (B) Raw relative expression (Cy3) microarray values of Hepc (solid line) and Hamp2 (dotted line) from birth through 14 weeks of age. (C) Body weight at weaning in WT and Cyp1b1−/− pups from dams fed the LF12 diet, LF12 + Iron diet or standard breeder diet (BD). (D) Hamp mRNA expression was measured by qPCR at weaning in WT and Cyp1b1−/− pups on the BD, LF12, and LF12 + Iron diet. Comparison between microarray and qPCR Hamp expression in WT and Cyp1b1−/− pups on the LF12 diet is highlighted. *p-value≤0.05, **p-value≤0.01