Table 2.

GVAD and Cyp1b1 deletion produce similar responses on high carbohydrate diets

Fold change upper versus	BD-HFD	Cyp1b1−/− LFD	LF12-HFD	GVAD-LF-12
lower	BD-LFD	BD-LFD	LF12-LF12	LF12-LF12
1B1-HF genes
Anxa5	−2.3*	−2.4*	−4.1**	−3.3**
Gas6	−2.2**	−2.1**	−3.7**	−1.8*
Cd52	−1.9**	−2.7**	−2.2	−2.5**
H2-Ab1	−1.5	−2.1**	−3.5*	−1.9**
H2-Eb1	−1.5	−2.2**	−2.9*	−1.9**
Mmd2	−4.6**	−3.9**	−5.5**	−9.5**
Klf6	−2.4**	−2.9**	−4.8**	−2.2*
Cidec	−1.9	−4.7	−35.1**	−4.3
Ly6d	−4.3**	−6.1**	−62.4**	−39.8**
Nupr1	−5.5**	−5.1**	−4.2**	−3.3**
Prodh	1.9*	2.2*	3.4**	2.2**
Rhoc	−2.5**	−2.8**	−7.4**	−3.1**
Uap1l1	−3.5**	−3.5*	−6.9**	−5.6**
Atf3	−3.1*	−2.9*	−6.7**	−5.9**
Spp1	−2.0	−2.6*	−3.4**	−3.6**
Cd63	−2.6*	−3.1*	−10.0*	−5.0**
Cxadr	−2.5*	−3.0**	−2.8**	−2.1**
Osbpl3	−3.3**	−14.1**	−8.6**	−4.3**
Diet Related
Gck	n.s.	n.s.	1.9*	1.5
Ppp1r3g	−2.4	−4.6**	−9.9**	−6.4*
Ppp1r3b	1.8	2.2	2.4	3.5**
Ppp1r3c	1.6	3.8**	n.s.	4.5**
Hamp	n.s.	n.s.	−1.6	−1.7
Hamp2	−1.6	−2.3*	1.6	6.5**

^*p-value ≤ 0.05

^**p-value ≤ 0.01

n.s. Non-significant values where the net FC < 1.5 and p-value > 0.05

Diet: Carbohydrate/Fat/Protein; BD: 55/22/23; HFD: 20/60/20; LFD: 70/10/20; LF12: 69/12.2/18.8