Table 5.

Neonatal metabolic gene stimulation is prevented by GVAD and Cyp1b1 deletion

Fold change upper versus	Weaning LF12	GVAD	Cyp1b1−/− LF12	Cyp1b1−/− GVAD
lower	Birth LF12	LF12	LF12	Cyp1b1−/− LF12
Hamp2	187.1**	−50.2**	−28.0**	3.7**
Fatty Acid Synthesis
Srebp-1c	4.9**	n.s.	n.s.	n.s.
Mlxipl/Chrebp	4.4**	n.s.	−2.6**	n.s.
Srebp2	1.5	n.s.	−1.5*	2.0**
Acaca	7.6**	−2.4**	−3.7**	1.5**
Acacb	7.9**	−3.0**	−12.3**	1.7*
Me1	8.4**	−4.1**	−3.6**	1.4*
Fasn	28.3**	−3.3**	−12.2**	2.7**
Scd1	86.9**	−4.3**	−12.2**	1.9
Elovl6	6.0**	−5.3**	−27.8**	2.8**
Acly	10.8**	−2.6**	−8.4**	1.5*
Mup4 a	73.8**	−3.9**	−7.3**	2.2**
Thrsp	136.6**	−1.7	−10.0**	4.6**
Cholesterol Metabolism
Acss2	8.6**	−3.5**	−7.0**	2.4**
Aacs	10.4**	−2.7**	−17.5**	4.5**
Idi1	4.7**	−1.6*	−10.6**	10.1**
Sqle	2.4*	−2.2**	−23.0**	26.0**
Hmgcr	4.0**	n.s.	−6.4**	4.2**
Lss	1.7*	n.s.	−3.4**	5.0**
Hmgcs1	3.5**	n.s.	−4.7**	3.8**
Cyp51	2.3*	−1.9*	−5.8**	7.2**
Fdps	4.1**	n.s.	−6.8**	8.0**
Sc4mol	3.5*	n.s.	−7.1**	7.9**
Fdft1	3.1**	n.s.	−1.9	2.2**
Dhcr7	3.7**	−1.6	−5.8**	3.6**
Gadd45γ	6.2**	−6.7**	−6.5**	2.1
Ppp1r3g	1.5	−9.4**	−7.3**	n.s.

^aAdditional Mup genes that follow the same expression pattern include: Mup1, Mup3, and Mup5

^*p-value ≤ 0.05

^**p-value ≤ 0.01

n.s. Non-significant values, FC<1.5 and p-value>0.05