Table 2.
Maternal primary outcomes
Diet (N = 200) | Metformin (N = 48) | Insulin (N = 101) | Metfom vs. diet P | Metfom vs.insulin P | Diet vs. insulin P | |
---|---|---|---|---|---|---|
HbA1c at 37 g.w. (mean) | 5.4 ± 0.9 | 5.3 ± 0.7 | 6.2 ± 1.8 | NS | < 0.01 | < 0.01 |
Fasting glycaemia mmol/l | 5.1 ± 0.9 | 5.3 ± 0.7 | 5.8 ± 1.4 | NS | <0.05 | <0.01 |
Postprandial glycaemia (PPG) mmol/l | 6.9 ± 1.6 | 7.0 ± 1.2 | 7.9 ± 1.9 | NS | <0.05 | < 0.05 |
Preeclampsia | 1 (0.5%) | 4 (8.3%) | 6 (6%) | < 0.01 | NS | < 0.01 |
Gestational age at delivery (g.w.) | 38.9 ± 1.9 | 38.9 ± 1.4 | 37.5 ± 2.2 | NS | < 0.01 | < 0.01 |
Mode of delivery -spontaneous | 86/130 (66.1%) | 22/46(47.8%) | 34/100 (34%) | < 0.05 | NS | < 0.05 |
- assisted | 3/130 (2.3%) | 0 | 0 | NS | NS | NS |
- caesarean section | 41/130 (31.5%) | 24/46(52.2%) | 66/100 (66%) | < 0.05 | NS | < 0.05 |