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. 2018 May 15;6(5):757–766. doi: 10.3889/oamjms.2018.168

Table 3.

In vivo antidiarrhoeal activity

Compound Dosage (mg/kg) The proportion of Weight of Watery Stool (%) The onset of Diarrhoea (hour) Total Number of Stools Number of Watery Stool Inhibition of Defecation (%) Inhibition of Diarrhoea (%)
Control - 83.07 ± 5.98 1.83 ± 0.31 16.33 ± 1.50 13.17 ± 2.06 0.0 0.0
Loperamide 4.2 42.49 ± 14.57* 3.67 ± 0.56* 6.83 ± 2.75* 3.83 ± 1.72** 58.16 70.89
EEZJ 400 77.34 ± 3.70ns 2.33 ± 0.21ns 11.17 ± 1.90ns 9.00 ± 0.97ns 31.63 31.66
EEZJ 800 73.00 ± 3.90ns 2.33 ± 0.33ns 10.50 ± 1.38ns 8.67 ± 1.01ns 35.70 34.17
EEZJ 1200 66.23 ± 12.06ns 2.83 ± 0.48ns 8.50 ± 1.82* 4.33 ± 1.45** 47.95 67.09

(means ± S.E.M; n = 6); ns P ≥ 0.05 compared to control (One-way ANOVA followed by Dunnett’s Test);

*

P ≤ 0.05 compared to control (One-way ANOVA followed by Dunnett’s Test);

**

P ≤ 0.01 compared to control (One-way ANOVA followed by Dunnett’s Test.