Table 7.
Group | Treatment | Dose (mg/kg) | Percentage of left paw oedema (%) after treatment (Mean ±SEM) | |||||
---|---|---|---|---|---|---|---|---|
1 h | 2 h | 3 h | 4 h | 5 h | 6 h | |||
1 | EEZJ | 800 | 12.67 ± 3.18** | 22.00 ± 7.55ns | 28.67 ± 6.33ns | 27.33 ± 5.55** | 30.33 ± 6.94** | 30.67 ± 4.41*** |
2 | EEZJ | 1200 | 7.00 ± 0.58*** | 15.00 ± 1.53* | 19.33 ± 0.88** | 19.00 ± 1.16*** | 22.67 ± 1.67*** | 19.67 ± 1.76*** |
3 | EEZJ | 1600 | 10.33 ± 0.33** | 19.67 ± 2.73ns | 25.00 ± 3.00* | 31.33 ± 1.20* | 28.00 ± 4.36** | 27.33 ± 3.53*** |
4 | Diclofenac Sodium | 100 | 3.00 ± 0.58*** | 6.00 ± 1.00** | 8.33 ± 0.67*** | 8.33 ± 1.33*** | 6.33 ± 1.33*** | 12.00 ± 7.69*** |
5. | Control | 100 | 22.33 ± 2.03 | 31.33 ± 1.67 | 40.33 ± 2.33 | 46.67 ± 2.67 | 53.33 ± 1.20 | 56.00 ± 2.08 |
Means ± S.E.M; n = 5); ns P = 0.05 compared to control (One-way ANOVA followed by Dunnett's Test);
P = 0.05 compared to control (One-way ANOVA followed by Dunnett's Test);
P = 0.01 compared to control (One-way ANOVA followed by Dunnett's Test);
P = 0.001 compared to control (One-way ANOVA followed by Dunnett's Test).