Table 3.
Activated Canonical Pathways (P < 0.05 and −2.2< z-Score >2.2) Observed in Human Ovarian Tissue from Developmental Days 47 and 137
| Canonical pathways | P | z-Scorea | Proteins |
|---|---|---|---|
| Fc γ receptor-mediated phagocytosis in macrophages and monocytes | 6.46E-04 | 3.16 | SRC, FYN, PRKCA, PLD3, YES1, CBL, HMOX1, DOCK1, ARPC1A, LYN |
| EGF signaling | 3.09E-02 | 2.24 | MAPK14, ITPR2, EGFR, SRC, PRKCA |
| LXR/RXR activation | 1.00E-04 | −3.46 | S100A8, TF, C3, FGA, FDFT1, AGT, CLU, SERPINF2, APOA1, SERPINA1, AHSG, TTR, ALB |
a
Positive z-scores denote samples with higher expression at 47 days of development, and negative values denote samples with higher expression at 137 days of development.