Table 1. Patient Clinical Characteristics.

Fx(s): fraction(s); GTV: gross tumor volume ; PBT: proximal bronchial tree;  PTV: planning target volume

	Case #1	Case #2	Case #3
Age (years)	66	87	69
Prescribed Dose # of Fxs	50 Gy in 4 fx	50 Gy in 5 fx	48 Gy in 4 fx
Primary Disease	Lung Adenocarcinoma	Lung Adenocarcinoma	Pancreatic Adenocarcinoma
Tumor Staging	T3N1M1a	T1bN0M0	Metastatic
Location within the Lung	Central	Peripheral	Peripheral
PTV Coverage Constraint	> 95% @ 50.0 Gy	> 95% @ 50.0 Gy	> 95% @ 48.0 Gy
Pulmonary Constraint #1	< 1500 cc @ 11.6 Gy (Both Lungs – GTV)	< 1500 cc @ 12.5 Gy (Both Lungs – GTV)	< 4 cc @ 15.6 Gy PBT
Pulmonary Constraint #2	N/A	< 1000 cc @ 13.5Gy (Both Lungs – GTV)	N/A
Spinal Cord Constraint #1	Max Dose < 26.0 Gy	Max Dose < 26.0 Gy	< 0.35cc @ 20.8 Gy
Spinal Cord Constraint #2	< 0.35 cc @ 20.8 Gy	< 0.25 cc @ 22.5 Gy	< 1.2 cc @ 13.6 Gy
Spinal Cord Constraint #3	< 1.2 cc @ 13.6 Gy	< 0.5 cc @ 13.5 Gy	N/A
Chest Wall / Ribs	N/A	Chest Wall < 30 cc @ 40.0 Gy	Ribs < 1 cc @ 32.0 Gy
Esophagus	< 5 cc @ 18.8 Gy	< 5 cc @ 27.5 Gy	< 5 cc @ 18.8 Gy
Heart	< 15 cc @ 28.0 Gy	< 15 cc @ 32.0 Gy	< 15 cc @ 28.0 Gy
GTV Volume Initial (cc)	6.91	41.39	1.91
GTV Volume Final (cc)	8.23	36.97	1.64
GTV Volume % Change	+19%	-11%	-14%